It all depends on what you need to have
If you are going to be retired, there are some great places North or South.
Some of the 'inland' cities like Moca, La Vega, San Francisco or Santiago or Mao have some interesting points. So do jarabacoa or moncion or Constanza...It all depends on your needs....
Health concerns? Then Santo Domingo or Santiago.
Beaches? Anywhere, just about, on the coast.
Golf? POP, Santiago, Santo Domingo, Juan Dolio, La Romana, Bavaro.
Up to you...
HB