Best is a subjective term. Hard to apply to a whole restaurant. Perhaps if you tell us what meal you are looking for we can come up with the "best" we've had or heard about. Anyone can do pasta but not everyone can do a good lasagna for example.
In Sosua , Bologna is my go to for Italian . and you can have Pizza and fine dining .
Opinions and recommendations, please!
Yesterday evening ca. Boca ChicaSosua/Cabarete traditionally is German area of influence. Italians never were very welcome here. For a whole variety of true Italian restaurants and Italian atmosphere with a live high quality music/songs go to Boca Chica. For German sausage, stake and beer - to Sosua.