New Alzheimer's drug approved in US

[chico bill]

A few members have posted that they are dealing with relatives with Alzheimer's
This new drug can stop the disease's progression.
How soon will it be until it is available from Biogen in the DR ?

Aducanumab Approved for Treatment of Alzheimer’s Disease

Get information and resources for Alzheimer's and other dementias from the Alzheimer's Association.

www.alz.org

 

[william webster]

I think it 'slows the progress' of the disease - not stop it.

Talk about an untested drug - and $56,000/yr
Add to that MRI's for possible brain swelling or bleeding, pre-testing, etc

This one I wouldn't touch

The testing was only on mild cases.... not advanced
Advanced case testing will be done in the real marketplace..... next phase

 

[william webster]

Here's a portion of the article


The approval “completely transforms” Biogen, said Brian Skorney, an analyst at Robert W. Baird & Company, who is projecting that the drug will generate $7.5 billion in revenue in 2025. “This changes it from a declining revenue company to a growth company,” he said, and, in so doing, “opens up a bit of Pandora’s box” in terms of pricing and reimbursement.

While only patients with mild cognitive decline were enrolled in the clinical trials, the F.D.A. approved the drug for anyone with Alzheimer’s, a much broader group of patients than many experts were expecting.

Just how lucrative the drug will be for Biogen will depend on how many patients it can reach — and in what circumstances, and for how long, insurers are willing to pay for it.

Dr. Steve Miller, the chief clinical officer at the insurer Cigna, said on Monday that he expected his company and most of its peers would pay for the drug only for patients with mild cognitive symptoms and higher-than-normal levels of the protein amyloid in their brains.

“There’s just no data that more advanced patients will benefit,” he said.

 

[playacaribe2]

A few members have posted that they are dealing with relatives with Alzheimer's
This new drug can stop the disease's progression.
How soon will it be until it is available from Biogen in the DR ?

Aducanumab Approved for Treatment of Alzheimer’s Disease

Get information and resources for Alzheimer's and other dementias from the Alzheimer's Association.

www.alz.org

A few members also posted that they have crypto currency....yet that thread was closed.

It was also established that Bitcoin can already be bought at ATM’s in the DR.

Why is this thread any different than that discussion.

They both have at least some connection to the DR.

And for the record, I happen to agree with you regarding some of these closures.


Respectfully,
Playacaribe2

 

[drstock]

I won't be taking this new drug any time soon. Although it is approved, it hasn't been tested enough for me, and I won't be a guinea pig. I have heard that it contains a microchip to allow Bill Gates to track you and will probably alter your genes to turn you into a Chinaman.

 

[windeguy]

My only sibling died of early onset Alzheimer's discovered at an age many years younger than I am now, and dead two years before my current age.
It was a long downward slide for him and the family.

One of 3 main reasons I retired at 48 and left the US for the DR going on 18 years ago.

I hope something worthwhile against it is eventually developed, with or without microchips.

 

[william webster]

Early Alzheimer's....

I know a girl who was institutionalized before 50 yrs of age.... that bad
Her mother had it too... later though

 

[chico bill]

My only sibling died of early onset Alzheimer's discovered at an age many years younger than I am now, and dead two years before my current age.
It was a long downward slide for him and the family.

One of 3 main reasons I retired at 48 and left the US for the DR going on 18 years ago.

I hope something worthwhile against it is eventually developed, with or without microchips.

How does Alzheimer's kill a person. I know this is a morbid topic, but why is it in the degeneration that becomes fatal ?
Is there a specialist in DR that deals with this disease.
I have a Dominican friend who has a parent showing symptoms - but no way her family could afford such an expensive drug

 

[chico bill]

I think it 'slows the progress' of the disease - not stop it.

Talk about an untested drug - and $56,000/yr
Add to that MRI's for possible brain swelling or bleeding, pre-testing, etc

This one I wouldn't touch

The testing was only on mild cases.... not advanced
Advanced case testing will be done in the real marketplace..... next phase

Maybe it will not be as expensive if sold in DR ? Likely we won't see such a drug here for several years, unless the Chinese steal it ?
I wonder if all the vaccinations for Covid will contribute to Alzheimer's increasing, but that is one of the causes that is blamed for the increased number of cases 'some say'

 

[La Profe_1]

How does Alzheimer's kill a person.

One of my sisters died of early onset Alzheimers's when she was 67, eleven years after being diagnosed. Her second daughter cared for her until "memory care" became necessary. My niece described it very simply by saying that her mother gradually forgot many things, but the last thing she forgot was how to swallow. Unable to swallow, she died very quickly at the end.

 

[chico bill]

Maybe it will not be as expensive if sold in DR ? Likely we won't see such a drug here for several years, unless the Chinese steal it ?

One of my sisters died of early onset Alzheimers's when she was 67, eleven years after being diagnosed. Her second daughter cared for her until "memory care" became necessary. My niece described it very simply by saying that her mother gradually forgot many things, but the last thing she forgot was how to swallow. Unable to swallow, she died very quickly at the end.

That is terrifying. I never knew swallowing wasn't a natural reflex.
I know it is not an easy disease to watch progress in loved ones.
My grandmother died of Parkinson's and that too is horrible and I have a niece now suffering from MS and she was just hospitalized in a psychiatric facility because she can not deal with the effects.
I did not know that MS caused such reactions but apparently dysphoria, anxiety and irritation are very common and depression among MS patients is pronounced.

 

[windeguy]

How does Alzheimer's kill a person. I know this is a morbid topic, but why is it in the degeneration that becomes fatal ?
Is there a specialist in DR that deals with this disease.
I have a Dominican friend who has a parent showing symptoms - but no way her family could afford such an expensive drug

I am not an expert, but the brain is very slowly shut down until it no longer controls the autonomic system.

My brother showed signs in his 50's and was put on anxiety medication because of a misdiagnoses. He slid into vegetative state for years and his body shut off at age 64. He was not in pain, but his family certainly was for all of those years.

 

[DR Solar]

My wife looked it up, $56,000.00 per year. I see an ocean voyage in my future.... less the boat.

 

[william webster]

Plus pre-studies
Plus MRI's to watch for bran bleeds or swelling

$56,000 is just the medicine - none of the peripherals

 

[keepcoming]

I watched my Dad die from it also my MIL's father here in DR. It slowly took away their ability to function. Eating became an issue, swallowing became an issue. Nerves to the brain began to shutdown, body/organs started to shutdown. Most think of the "not remembering / confused" part of the disease. But when the disease has progressed it is a very sad process to witness.

 

[slowmo]

My wife looked it up, $56,000.00 per year. I see an ocean voyage in my future.... less the boat.

Sounds like there is some push back already to lower the price, especially given concerns about how effective the drug actually is at slowing down the disease.