@Eldie
From Santiago is an easy process:
- You can take Javilla Tours bus that goes Santiago-Puerto Plata highway. They have 2 buses (express to POP and the ones with stops; take the second). The main entrance to Saltos de Damajagua is just right in the highway, very walkable, before Imbert. Less than 200 pesos.
★★★★★ · Tourist attraction
maps.app.goo.gl
- Buses departs every 1 hour from Santiago starting 5:30am. And they're available on the highway until 6pm.
- You'll be in Damajagua in about an hour.
With Uber the process will be easier, and even agree with the driver to wait for you when you finish.. but expect higher fares, as the waterfalls are in the middle of the countryside and fares are higher.
Best of luck!