The museum is already getting good reviews, after its inaugural by President Leonel Fernandez in June 2012. The Casa Museo General Gregorio Luperon was built to commemorate the General Gregorio Luperon (1839-1897), the army general and politician who is recognized for his role in restoring Dominican independence after the annexation to Spain in 1863. The annexation occurred after Dominican leaders feared Haitian leaders would again dominate the country. The invading Haitian government had been expelled during the 1844 independence war. The museum is located where Luperon last lived in a Victorian-style house located on Calle 12 de Julio almost corner Padre Castellanos in downtown Puerto Plata.
Construction works were entrusted to engineer Huberto Perez and architect Sarah Garcia and museum expert Margarita Gonzalez was the curator for the exhibits. The museum cost of RD$80 million was funded by the government.
On exhibit are the boots and cap of General Luperon, his furniture, books, and even his legendary sword. He was provisional President of the Republic from 1879-1880. He also is remembered for his support to General Maximo Gomez who fought the Cuban independence war.
The Puerto Plata International Airport is named for him.