Ensanchez Libertad is close to Monterrico, which is just before Cienfuego.
I would rate it fairly safe, a little more safer then Cienfuego.
I have many friends there also and have not had any problems.
In four years, no incidences, usually there about everyday.
Again, I do not travel (prowl) around in Santiago at night.
Prior to my getting a car about 4 years ago, I walked almost every section of Santiago, with no problems (Went through a few pairs of shoes). And I do mean walked all over the city. Complete circle, and along all the major roads and through many barrios. Even to PriceSmart. I also rode every OMSA bus from one end to the other end of every route they have. (To get to learn the city more)
I am a gringo (Rubio?), spotted as an Americano a block away, no problems.
It's all in your attitude, use common sense and you should be fine.
I didn't always have the Uzi! Just joking!
Map of the area (My map is from 1991)
I made the map a link, as it is too wide to post directly in this reply.
Ensanchez Libertad