I'm sure the move will take some time to adjust to, but do give it time. You won't regret it. I have lived all over the Caribbean in the last twenty years and it was always difficult moving to a new local. I don't live full time in Santo Domingo but visit there often. I maintain an apartment in the Zona Oriental area of the city and have gotten to know a lot of fun, trust-worthy people in SD. Every time I visit SD I have an absolute blast!
Santo Domingo has a lot to offer. It has superb nightlife, supermarkets, department stores, and I believe, the prettiest girls in the Caribbean. (I know, i have read all the threads about Santiago chicas, but SD chicas are hard to beat!)
It took a while for SD to grow on me, but grow on me it has. I now spent all my time off nowhere else but in Santo Domingo!